Led by fifth-year head coach Andy Enfield, they played their home games at the Galen Center in Los Angeles, California as members of the Pac-12 Conference.

They were one of the last four teams not selected for the NCAA tournament and as a result earned a No.

They defeated Washington in the first round of the Pac-12 tournament before losing in the quarterfinals to UCLA.

On September 26, federal prosecutors in New York announced charges of fraud and corruption against 10 people involved in college basketball, including USC assistant coach Tony Bland.

[3] Potential 2018 NBA draft pick De'Anthony Melton would be indefinitely suspended in relation to the scandal in January before leaving USC on February 21, 2018.