Led by head coach Jay Wright in his 17th year, the Wildcats played their home games at the Wells Fargo Center in Philadelphia, Pennsylvania as members of the Big East Conference.

[4] They defeated Radford,[5] Alabama,[6] West Virginia,[7] and Texas Tech to advance to the Final Four for the second time in three years.

[13] The Wildcats' home court, The Pavilion, underwent a temporary closure for a $60 million renovation project during the season.

[17] The exception was the November 29, 2017 game with Big 5 rival Penn; it was instead held at Jake Nevin Field House, which had been home to the team before the Pavilion's initial 1986 opening.

[22] Villanova was picked to win the Big East in the conference's preseason Coaches' Poll for the fourth consecutive year.