In the NLWC Game, they defeated the Colorado Rockies to advance the NLDS against the division rival Los Angeles Dodgers.

[2] Facing the Los Angeles Dodgers on September 4, Diamondbacks outfielder J. D. Martinez became the 18th player in MLB history to hit four home runs in a game.

The play was considered a major highlight in their first Wild Card game in franchise history, winning 11–8 that night at home.

The Diamondbacks also became the first team to record 4 triples in a single playoff game since the Boston Americans in the 1903 World Series.

Infielders Coaches First baseman Paul Goldschmidt won his third Silver Slugger Award as the best offensive player at his position in the National League.