Defending champion Simona Halep defeated Kristina Mladenovic in the final, 7–5, 6–7(5–7), 6–2 to win the women's singles tennis title at the 2017 Madrid Open.

As a result of Serena Williams' withdrawal due to pregnancy, Angelique Kerber regained the WTA no.

1 ranking at the end of the tournament.

Click on the seed number of a player to go to their draw section.