Regular season conference play began in December 2018 and concluded in March 2018.

The Big 12 tournament was held from March 13 through 16 at the Sprint Center in Kansas City, Missouri.

Texas Tech advanced to the NCAA championship game where they lost to Virginia.

There were no head coaching changes following the 2017–18 Big 12 Conference men's basketball season.

Big 12 Preseason Poll Pre-Season All-Big 12 Team To earn "consensus" status, a player must win honors from a majority of the following teams: the Associated Press, the USBWA, Sporting News, and the National Association of Basketball Coaches.