The 2018–19 Caloocan Supremos season was the second season of the franchise in the Maharlika Pilipinas Basketball League (MPBL).
[1] Caloocan improved from their one-win season in win percentage with their third win against the GenSan Warriors.
After going 4–12 in their first sixteen games, the team would win seven of the remaining nine games, finishing the regular season with an 11–14 record.
This includes a win against Pampanga Lanterns, which helped the team clinch the final playoff spot as both teams were tied for 8th.
They would lose in the Division Quarterfinals to the Bataan Risers in two games.