The 2018–19 Club Puebla season is the club's 72nd professional season in Mexico's top-flight football league.

The season is split into two tournaments—the Torneo Apertura and the Torneo Clausura—each with identical formats and each contested by the same eighteen teams.

Players and squad numbers last updated on 6 January 2019.

[2]Note: Flags indicate national team as has been defined under FIFA eligibility rules.

Source: LigaMX Puebla's Home Attendance[5] by round, Estadio Cuauhtémoc has a capacity of 51,726.