The winners were assured a place in the 2019–20 UEFA Europa League group stage, and both they and the runners-up automatically qualified for the four-team 2020 Supercopa de España.

Barcelona entered the competition as four-time defending champions in an attempt to conquer an unprecedented fifth consecutive title.

The Catalans reached the final for the sixth time in a row, but were beaten by Valencia 2–1 who achieved their eighth title overall and the first since 2008.

[4] Due to the breach of the competition rules, giving byes to unauthorised teams, the draw of the first and second round had to be partially repeated.

[5] Fuenlabrada Navalcarnero Internacional Rápido de Bouzas Unionistas Cultural Leonesa Compostela Mensajero Mirandés Langreo Racing Santander Gimnástica Torrelavega Barakaldo Cultural Durango Gernika Calahorra Tudelano UD Logroñés Mutilvera Lleida Esportiu Badalona Cornellà Castellón Ontinyent Teruel Ebro Conquense Sant Andreu Poblense Talavera de la Reina Melilla Marbella Cartagena Murcia Lorca FC UCAM Murcia Don Benito Villanovense Jaén Ceuta Yeclano During the draw, Villanovense, Murcia, Badalona, Tudelano and Lorca FC received a bye to the second round.

The draw for the Round of 32 was held on 19 October 2018 at La Ciudad del Fútbol, Las Rozas de Madrid.

The draw for the round of 32 took place on 19 October at La Ciudad del Fútbol, in Las Rozas de Madrid.