Aris Limassol and Ethnikos Achna were relegated at the end of the first phase of the 2017–18 season after finishing in the bottom two places of the table.
They were joined by Olympiakos Nicosia, who finished at the bottom of the second-phase relegation group.
The relegated teams were replaced by 2017–18 Second Division champions Enosis Neon Paralimni.
Note: Flags indicate national team as has been defined under FIFA eligibility rules.
In order to preserve chronological progress, any postponed matches are not included in the round at which they were originally scheduled, but added to the full round they were played immediately afterwards.