The 2018–19 Duquesne Dukes men's basketball team represented Duquesne University during the 2018–19 NCAA Division I men's basketball season.

The Dukes, led by second-year head coach Keith Dambrot, played their home games at the A. J. Palumbo Center in Pittsburgh, Pennsylvania as members of the Atlantic 10 Conference.

They finished the season 19–13, 10–8 in A-10 Play to tie for 6th place.

They lost in the first round of the A-10 tournament to Saint Joseph's.

10 seed in the A-10 tournament, they lost Richmond in the second round.