The season started on 11 October 2018 and finished in May 2019 with the 2019 EuroLeague Final Four at Fernando Buesa Arena in Vitoria-Gasteiz, Spain.

[1] The labels in the parentheses show how each team qualified for the place of its starting round (TH: EuroLeague title holders).

Herbalife Gran Canaria qualified as the highest-placed team in the Liga ACB without a long-term EuroLeague licence.

The four remaining teams play a single knockout round on Friday evening, with the two winners advancing to the championship game.

[32][33] Source: EuroLeagueNotes:1: 2017–18 season average applied to EuroCup games 2: AX Armani Exchange Olimpia played one match at PalaBancoDesio, instead of Mediolanum Forum.