A total of 20 teams from 11 countries participated in the 2018–19 EuroLeague Women.

[3] League positions of the previous season shown in parentheses (TH: EuroLeague Women title holders): The draw was held on 5 July 2018 at the FIBA headquarters in Munich, Germany.

[4][5] The regular season started on 24 October 2018 and ended on 20 February 2019.

If teams are level on record at the end of the Regular Season, tiebreakers are applied in the following order:

This year the regular season awards decided by fan vote.