The 2018–19 European Rugby Challenge Cup pool stage is the first stage of the competition in the fifth season of the European Rugby Challenge Cup.
The pool stage begins on 13 October 2018 and is due to be completed on 18 January 2019.
The draw will take place on 20 June 2018 in the Olympic Museum, Lausanne, Switzerland.
Teams in the same pool will play each other twice, both at home and away in the group stage, that will begin in October 2018, and continue through to January 2019, before the pool winners and three best runners-up progressed to the quarter-finals.
Teams will be awarded competition points, based on match result.