The 2018–19 IUPUI Jaguars men's basketball team represented Indiana University – Purdue University Indianapolis during the 2018–19 NCAA Division I men's basketball season.

The Jaguars, led by fifth-year head coach Jason Gardner, played their home games at Indiana Farmers Coliseum in Indianapolis, Indiana as second-year members of the Horizon League.

They lost in the quarterfinals of the Horizon League tournament to Wright State.

They lost in the quarterfinals of the Horizon League tournament to Oakland.

The season marked the first season as members of the Horizon League as IUPUI replaced Valparaiso who left to join the Missouri Valley Conference.