The 2018–19 Indiana State Sycamores basketball team represented Indiana State University during the 2018–19 NCAA Division I men's basketball season.

The Sycamores, led by ninth-year head coach Greg Lansing, played their home games at the Hulman Center in Terre Haute, Indiana as members of the Missouri Valley Conference.

ISU coach Greg Lansing began the season needing two wins during the season to surpass his mentor (Royce Waltman) on the ISU Coaching Leaderboard.

Lansing passed Waltman following the Sycamores victory over the McKendree Bearcats and is currently second (148) in wins at Indiana State; the leader Duane Klueh has 182.

Junior Guard Jordan Barnes became the 39th member of the ISU 1,000-pt Club.