The 2018–19 Jackson State Tigers basketball team represented Jackson State University during the 2018–19 NCAA Division I men's basketball season.

The Tigers were led by sixth-year head coach Wayne Brent, and played their home games at the Williams Assembly Center in Jackson, Mississippi as members of the Southwestern Athletic Conference.

6 seed Alabama State in the quarterfinals.

Due to Grambling State's ineligibility, they received the No.

5 seed in the SWAC tournament where they lost to Southern in the quarterfinals.