The 2018–19 La Salle Explorers basketball team represented La Salle University during the 2018–19 NCAA Division I men's basketball season.

The Explorers, led by first-year head coach Ashley Howard, played their home games at Tom Gola Arena in Philadelphia, Pennsylvania as members of the Atlantic 10 Conference.

[1] On March 23, 2018, head coach John Giannini and the school mutually agreed to part ways after 14 seasons.

[2] Giannini left with a 212–226 record at La Salle.

On April 8, the school hired Villanova assistant Ashley Howard as head coach.