The season began on 20 July 2018 and ended on 2 June 2019, being the fourth to take place since the play-off/play-out rule has been introduced.
Dunărea Călărași and Hermannstadt joined as the promoted clubs from the 2017–18 Liga II.
CFR Cluj managed to defend the title for the first time in their history, while FCSB became the first team in the country to finish as runners-up for four consecutive seasons.
Midfielders: Mihai Bordeianu (26 / 1); Valentin Costache (18 / 1); Emmanuel Culio (25 / 5); Ciprian Deac (26 / 4); Damjan Đoković (33 / 4); Ovidiu Hoban (12 / 1); Alexandru Ioniță (23 / 2); Cătălin Itu (1 / 0); Sebastian Mailat (10 / 0); Mate Maleš (8 / 0); Thierry Moutinho (16 / 1); Adrian Păun (27 / 3); Claudiu Petrila (5 / 0).
Forwards: Júlio Baptista (2 / 0); Cristian Bud (4 / 0); Giuseppe De Luca (3 / 0); Billel Omrani (32 / 6); Robert Tambe (6 / 0); George Țucudean (27 / 8); Urko Vera (2 / 0).
(league appearances and goals listed in brackets) Manager: Edward Iordănescu / Toni Conceição / Alin Minteuan / Dan Petrescu.