[12] However, their FA Cup third round exit at the hands of Newcastle United in January was followed up with a run of four wins from 12 league matches, which meant they relinquished first position once again in March.

[23] The team recorded their first point of the season after drawing 1–1 at home to Sunderland, who took the lead shortly before half-time through Josh Maja with a shot into the bottom corner, before Matty Pearson equalised on 68 minutes from Alan Sheehan's cross.

[26] Their first win of the season came after a 2–0 home victory over Southend United, in which Elliot Lee scored from seven yards to give Luton a second-minute lead after a shot from Pelly Ruddock Mpanzu deflected into his path.

[27] Luton recorded a second successive home win after beating Shrewsbury Town 3–2, the away team taking the lead through a 23rd-minute penalty scored by Shaun Whalley.

[28] Jorge Grant levelled the score early into the second half with a free kick from 20 yards, before Lee Angol restored Shrewsbury's lead 15 minutes later after capitalising on a mistake by James Shea.

[35] A 2–1 defeat away to Doncaster Rovers saw Luton's four-match unbeaten run come to an end, with the home team taking the lead in the sixth minute through Matty Blair.

[36][37] Lee equalised with a header shortly before half-time, and Ben Whiteman scored the winner for Doncaster less than a minute into the second half with a deflected 20-yard shot.

[41][42] After going behind to Tariqe Fosu's 23rd-minute penalty, Luton scored two second half goals through Harry Cornick and James Collins, before Chris Solly equalised for Charlton with a volley in the fifth minute of stoppage time.

[44] Ricky Holmes gave the home team the lead early in the second half, before Luton equalised through Collins who followed up for the rebound after Cornick's shot had hit the crossbar from Mpanzu's cross.

[45] Luton progressed to the second round of the EFL Trophy as Southern Group H winners after a 3–0 home win over Milton Keynes Dons, in which they took the lead in the 17th minute when Sheehan scored a penalty after David Kasumu tripped Shinnie.

[58] Justin extended the lead six minutes later, and won a penalty in first-half stoppage time converted by Collins, which made the half-time score 4–0.

[69][70] Midfielder Drew Richardson, a first-year scholar, joined Isthmian League Premier Division club Harlow Town on work experience for one month.

[74] Luton's first result of 2019 was a 0–0 home draw with Barnsley, with the best chance of the match coming from Lee's 20-yard shot which was saved by goalkeeper Adam Davies.

[83] Luton were knocked out of the FA Cup after losing 1–0 at home to Sheffield Wednesday in a third round replay, who scored their goal a minute into the second half through Atdhe Nuhiu.

[84] Barnsley midfielder George Moncur was signed on a two-and-a-half-year contract for an undisclosed fee,[85] and Jack James joined Havant & Waterlooville of the National League on a one-month youth loan.

[86] Luton moved to within a point of Portsmouth once more with a 4–0 home win over Peterborough United, courtesy of a Collins hat-trick and Luke Berry's first goal of the season.

[87][88] Defender Toby Byron, a second-year scholar, joined Southern League Premier Division Central club Hitchin Town on work experience for one month.

[92] Queens Park Rangers defender Alex Baptiste, Nottingham Forest and Scotland international striker Jason Cummings, and Brighton & Hove Albion striker Aaron Connolly, a Republic of Ireland under-19 international, were signed on loan for the rest of 2018–19,[94] while Lloyd Jones, Jack Senior and Jarvis were loaned to Plymouth, Harrogate Town and Falkirk respectively until the end of the season.

[98] This was followed by another 3–0 victory, this time at home to Wycombe Wanderers, which meant Luton equalled a club record of 19 matches unbeaten in the Football League.

[107] Stacey scored in the 16th minute from a low shot as Luton beat Bradford City 1–0 away,[108] and the result meant the team set a new club record of 12 away matches unbeaten in the Football League.

[110] Luton were held by Gillingham to a 2–2 home draw, in which they took the lead shortly before half-time through Hylton, before Tom Eaves equalised for the away team with a header early in the second half.

[113] Luton took a two-goal lead through Collins and Berry, before Jonson Clarke-Harris scored a consolation goal for Bristol Rovers in first-half stoppage time.

[119] Collins restored Luton's lead on 39 minutes with a powerful header, before Steve Seddon scored AFC Wimbledon's equaliser in second-half stoppage time.

[119] Luton's final away match of the season ended in a 2–1 defeat to Burton Albion, resulting in the team only being above second-placed Barnsley on goal difference.