The 2018–19 Notre Dame Fighting Irish women's basketball team represented the University of Notre Dame during the 2018–19 NCAA Division I women's basketball season.

The Fighting Irish, led by 32nd year head coach Muffet McGraw, played their home games at Edmund P. Joyce Center as members of the Atlantic Coast Conference.

They were runners up in the ACC women's tournament losing to Louisville in the final game.

They received an at large bid for the NCAA women's tournament as a number one seed.

They won the tournament beating other number one seeds, Connecticut and Mississippi State along the way.