Ten teams from seven countries (Belarus, Croatia, North Macedonia, Serbia, Slovakia, Bosnia and Herzegovina and Romania) were participating in this year's competition.

The SEHA League consists of two phases – the first one has 18 rounds in which all teams played one home and one away games against each other.

RK Vardar defeated PPD Zagreb 26–23 in the final to win their fifth title.

Following is the list of clubs competing in 2018–19 SEHA League, with their manager, team captain, kit manufacturer and shirt sponsor.

The SEHA - Gazprom League Executive Committee had made the decision for the final four tournament to be held at the Universal Sports Complex Victoria in Brest, Republic of Belarus, on 2nd and 3 April.