The 2018–19 season was the 118th season in Società Sportiva Lazio's history and their 31st consecutive season in the top-flight of Italian football.

Lazio competed in Serie A, the Coppa Italia and the Europa League.

The season was coach Simone Inzaghi's third in charge of the club, having led Lazio to consecutive fifth-placed finishes in the 2016–17 and 2017–18 seasons.

Lazio won the 2018–19 Coppa Italia 2–0 over Atalanta, winning their seventh title overall.

Source: Competitive matches