The 2018–19 Saint Mary's Gaels women's basketball team represented Saint Mary's College of California in the 2018–19 NCAA Division I women's basketball season.

The Gales, led by thirteenth year head coach Paul Thomas, played their home games at the McKeon Pavilion and were members of the West Coast Conference.

They finished the season 21–12, 12–6 in WCC play to finish in fourth place.

They advanced to the semifinals of the WCC women's tournament, where they lost to Gonzaga.

They received an at-large bid to the Women's National Invitation Tournament, where they defeated Hawaii in the first round before losing to WCC member Pepperdine in the second round.