The 2018–19 season was the 116th in the history of the Southern League since its establishment in 1894.
The league (known as Evo-Stik League Southern, following a sponsorship deal with Evo-Stik) has two Premier divisions (Central and South) at step 3 of the National League System (NLS) and two Division One divisions (Central and South) at step 4 of the NLS.
[1] This was the first season to consist of four divisions in the league, following a shakeup of the Southern, Isthmian, and Northern Premier Leagues divisions by geographical region.
The Premier Division Central consisted of ten clubs from the previous season Premier Division, and twelve new clubs.
The Premier Division South consisted of ten clubs from the previous season Premier Division, and twelve new clubs.