The winners of the competition will secure a spot in the second qualifying round of the 2019–20 UEFA Europa League, unless they had already qualified for European competition in the 2019–20 season, in which case the qualification spot will go to fourth-placed team of the 2018 Allsvenskan.
A total of 96 clubs will enter the competition, 64 teams from district sites and 32 from the Allsvenskan and the Superettan.
64 teams from the third tier or lower of the Swedish league system competed in this round.
The draw was held on July 7, 2018 with games scheduled to be played on August 21–23, 2018.
The ranking of the 16 seeded teams was decided by league position in the 2018 season.