[1] KCCA FC won the championship with two games left to play in the home and away season, after drawing 1–1 with Ndejje University.
[2] UPDF, Proline FC and Masavu FC Entebbe were relegated from the 2017–18 Uganda Premier League.
They were replaced by Nyamityobora FC, who won the Rwenzori group of the 2017–18 FUFA Big League,[3] Ndejje University, and Paidha Black Angels, who won the promotion playoff.
[4] All three promoted teams would be relegated this season.
Some of the Kampala clubs may on occasions also play home matches at the Mandela National Stadium.