The women's 100 metres event at the 2018 African Championships in Athletics was held on 1 and 2 August in Asaba, Nigeria.
[1] Qualification: First 3 of each heat (Q) and the next 4 fastest (q) qualified for the semifinals.
Wind:Heat 1: +0.4 m/s, Heat 2: 0.0 m/s, Heat 3: -0.5 m/s, Heat 4: -1.4 m/s Qualification: First 3 of each semifinal (Q) and the next 2 fastest (q) qualified for the final.
Wind:Heat 1: -0.9 m/s, Heat 2: -2.4 m/s Wind: -2.3 m/s