[10] Voting for the Parliament was on the basis of universal suffrage, which comprised all nationals over 18 years of age, registered in Andalusia and in full enjoyment of their political rights.

[11] The 109 members of the Parliament of Andalusia were elected using the D'Hondt method and a closed list proportional representation, with an electoral threshold of three percent of valid votes—which included blank ballots—being applied in each constituency.

[10][12][14] The president had the prerogative to dissolve the Parliament of Andalusia and call a snap election, provided that no motion of no confidence was in process and that dissolution did not occur before one year had elapsed since the previous one.

[16][17] On 3 July, ABC hypothesized on the actual chances of an early election taking place, dubbing it as a real possibility after considering that Díaz would seek to capitalize on the Spanish Socialist Workers' Party (PSOE)'s growing popularity in opinion polls, hoping to benefit from the disarray within the People's Party (PP) ranks—resulting from its national leadership contest—and Citizens (Cs)'s inability to react after the motion of no confidence which ousted Mariano Rajoy's government from power.

As a result of the election, the ruling Spanish Socialist Workers' Party of Andalusia (PSOE–A) suffered a severe setback, plummeting in traditional strongholds where abstention rates skyrocketed and underperforming all opinion polls published throughout the campaign.

[46][47] Together with the left-wing Forward Andalusia (AA) alliance, which failed to garner the combined support of Podemos and United Left (IULV–CA) at the 2015 election, it commanded just 50 seats, five short of a majority, bringing the Socialists on the verge of losing the Regional Government after 36 years of uninterrupted rule.

[50][51] Concurrently, Vox's result signalled the first time a far-right party had won seats in a regional parliament in Spain since the country's return to democracy, following the death of longtime dictator Francisco Franco in 1975.

[59][60][61] Concurrently, the fragmentation within the centre-right to right-wing electorate was also noted as a remarkable event, as the PP's decades-long, unquestioned dominance over such spectrum came to an end.

[64][65] Concurrently, Cs leaders showed reticence to allying themselves with Vox, instead claiming their right to attempt to form a government of their own with PP and PSOE support "without ruling out any other options".

[66][67][68] Still incumbent President Susana Díaz urged for an alliance of democratic forces to form around her party in order to "build a firewall against the extreme right",[69][70] but her chances of retaining power were regarded as slim.

[71][72] Díaz ruled out a resignation as she "had won [the election]", reasserting her will to continue leading the PSOE–A and attempt forming a government with the support of any of the other parties but Vox.

[78][79] Within a few days from the election, both PP and Cs candidates, Juanma Moreno and Juan Marín clashed on the issue of who should lead the Regional Government.

The PP warned Marín that failing to support Moreno would mean a new regional election, anticipating that it would lead to a massive mobilization of PSOE–A voters who had abstained.

[80][81] The Cs leadership showed a willingness to enter negotiations with PP if it was to elect Marín as president, but the party was weary of having to rely on the support of far-right Vox and instead kept their offer for an—unlikely—support or abstention from the PSOE.

[87] Both PP and Cs had been negotiating a formal agreement made of 90 core proposals, some of which—such as their promise to fully apply gender equality laws or the approval of various measures aimed at violence against women-prevention—went against Vox's own electoral manifesto.

[90][91] On 8 January 2019, Vox published a list of 19 demands in exchange for supporting a centre-right government, including cuts in the regional self-government, a repeal of regional legislation affording special protection to women and LGTBI groups, and the creation of new laws to protect bullfighting, hunting and "popular culture and traditions", as well as the deportation of 52,000 undocumented migrants and the elimination of public subsidies for "supremacist feminism" and for "Islamic associations".

[105] The PSOE–A initially announced that Susana Díaz would run for investiture and called for Cs to join "a democratic bloc" against the far-right, whereas Adelante Andalucía showed a willingness to support any alternative candidate to prevent a Vox-influenced government.