The second round of CAF matches for 2018 FIFA World Cup qualification was played from 11 to 17 November 2015.
The draw for the second round was held as part of the 2018 FIFA World Cup Preliminary Draw on 25 July 2015, starting 18:00 MSK (UTC+3), at the Konstantinovsky Palace in Strelna, Saint Petersburg, Russia.
[2][3][4] The seeding was based on the FIFA World Rankings of July 2015 (shown in parentheses).
Ivory Coast won 4–0 on aggregate and advanced to the third round.
Gabon won the penalty shoot-out 4–3 and advanced to the third round.
Burkina Faso won 3–2 on aggregate and advanced to the third round.