The fifth round (also known as the Hexagonal or Hex) of CONCACAF matches for 2018 FIFA World Cup qualification was played from 11 November 2016 to 10 October 2017.

[1][2] Mexico, Costa Rica, and Panama qualified for the 2018 FIFA World Cup, while Honduras advanced to the inter-confederation play-offs.

The United States (who failed to qualify for the World Cup for the first time in 32 years) and Trinidad and Tobago were eliminated in this round.

The United States, Mexico, and Costa Rica have qualified for every "Hex" since it first began in 1998.

The draw for the fifth round (to decide the fixtures) was held on 8 July 2016, 10:00 EDT (UTC−4), at the CONCACAF headquarters in Miami Beach, United States.