The 2018 Grote Prijs Jef Scherens was the 52nd edition of the Grote Prijs Jef Scherens road cycling one day race in and around Leuven.

[1] It was held on 16 September 2018 as a 1.1 categorised race and was part of the 2018 UCI Europe Tour and the 2018 Belgian Road Cycling Cup.

Leuven-born Jasper Stuyven won the group in a bunch sprint ahead of Jonas van Genechten and defending champion Timothy Dupont.

Twenty-three teams were invited to take part in the race.

UCI WorldTeams UCI Professional Continental Teams UCI Continental Teams This cycling race article related to Belgian cycling is a stub.