The 2018 L'Open 35 de Saint-Malo was a professional tennis tournament played on outdoor clay courts.

It was the twenty-third edition of the tournament and was part of the 2018 ITF Women's Circuit.

It took place in Saint-Malo, France, on 17–23 September 2018.

The following players received a wildcard into the singles main draw: The following players received entry from the qualifying draw: The following players received entry as lucky losers: