The 2018 MPBL playoffs, also known as the MPBL Anta–Rajah Cup playoffs, was the postseason tournament of the Maharlika Pilipinas Basketball League's inaugural 2018 season.
It began on March 20, 2018, three days after the regular season, and ended on April 10, 2018 where the Batangas City Athletics beat the Muntinlupa Cagers in the 2018 MPBL finals.
Seeding was based on winning percentage, with tiebreaker rules applied should multiple teams have the same record.
During the first two rounds, two games were played in a gameday, with homecourt advantage alternating between the higher-seeded teams of each series.
All playoff games this season were aired on ABS-CBN's S+A channel as part of its broadcast rights with the league.