The 13th running of the Omloop Het Nieuwsblad women's race in Belgium was held on 24 February 2018.

Widely regarded as the start of the Classics season, it was a 1.1 event of the women's international calendar.

The total distance was 122.1 km (75.9 mi), covering eight classified climbs in the Flemish Ardennes.

[1] Danish rider Christina Siggaard claimed a surprise win in the sprint of a 25-strong group.

American Alexis Ryan finished second, Italian Maria Giulia Confalonieri third.