The tournament continued to use the same sequence of games across the schedule, starting on 18 August with Australia hosting reigning champions New Zealand and South Africa hosting Argentina, and ending after eight weeks (six rounds and two bye weeks) on 6 October when New Zealand visited South Africa and Australia played in Argentina.

[10] 1 Ahead of the traveling to South Africa for the opening match, Tomás Lezana joined the squad after recovering from injury.

[14] 5 On 19 September, Ramiro Herrera, Matías Osadczuk, Lucas Paulos and Enrique Pieretto joined were added as part of the training squad ahead of the fifth round clash with New Zealand.

[19] Liam Coltman and Ngani Laumape were included in the squad as injury covers for Dane Coles and Sonny Bill Williams respectively.

2 On 30 August, Angus Ta'avao joined the squad as an injury replacement for Joe Moody who was ruled out of the rest of the Championship.

[22] 1 On 31 August, Schalk Brits, Damian de Allende and Cheslin Kolbe were added to the squad ahead of the Australasian leg of the Championship in rounds 3 and 4.