The team will also have a new head coach this season, with Anthony Pulis coming over from Orlando City B. Saint Louis revealed their preseason schedule on January 18.

They announced six games over a span of about a month, with three coming against collegiate programs, two against an adult amateur club, and one against a fellow professional team.

[3] The expansion was spurred by the addition of six new clubs for the 2018 season: Atlanta United 2, Fresno FC, Indy Eleven, Las Vegas Lights, Nashville SC, and North Carolina FC.

On January 14, 2018, the league announced home openers for every club.

Saint Louis will play three times against Swope Park Rangers and Tulsa Roughnecks.