Angelique Kerber defeated Serena Williams in the final, 6–3, 6–3 to win the ladies' singles tennis title at the 2018 Wimbledon Championships.

[1][2] Williams was attempting to equal Margaret Court's all-time record of 24 major singles titles, and to become the first mother to win a major singles title since Kim Clijsters won the 2011 Australian Open.

Garbiñe Muguruza was the defending champion, but lost in the second round to Alison Van Uytvanck.

[3] Simona Halep, Caroline Wozniacki and Sloane Stephens were in contention for the world No.

[5][6] This was also the first time in the Open Era that none of the top four women's singles seeds reached the fourth round at Wimbledon.