Some of the largest rallies in the United States were held in New York, Washington, Los Angeles, Dallas, Philadelphia, Chicago, San Francisco, and Atlanta.

The mission that the march is aimed towards is to gather the political power of diverse women and their communities to create a change in the society.

[8][11] In Washington, D.C. thousands gathered at the Reflecting Pool at the Lincoln Memorial, although the number of individuals who attended was lower than the previous year's march.

Speakers included Michael Moore, Whoopi Goldberg, Padma Lakshmi, Amy Schumer, Laura Benanti, Amber Tamblyn, Patricia Arquette, Rosie Perez, Piper Perabo, Drew Barrymore, and singers Cyndi Lauper and Halsey.

Due to the circumstances in Washington, D.C., a few of the planned speakers were unable to show up, including Senator Maggie Hassan and Congresswoman Annie Kuster.

[26] In Carytown in Richmond, the capital of the Commonwealth of Virginia, newly elected Governor Ralph Northam participated in the Women's March.

[28][29] Hundreds of protesters marched outside Mar-a-Lago in Palm Beach, Florida, although the President was not there as planned, due to the government shutdown.

[3] On January 21, the organization Women's March Incorporated hosted a rally, Power to the Polls, in Las Vegas.

[39] Instead of a traditional speech, Halsey performed a five-minute poem titled A Story Like Mine, in which she talked about sexual assault and violence she and others had experienced.

"[41][40] Halsey's speech, along with others, were intended to prompt women to reflect and debate misogynistic and patriarchal societal values.

"[41] Halsey completed her speech by requesting all—"Black, Asian, poor, wealthy, trans, cis, Muslim, Christian"—sexual assault victims to listen and support each other.