The 2019–20 Arab Club Champions Cup knockout stage began on 20 August 2019 and ended on 21 August 2021 with the final at the Prince Moulay Abdellah Stadium in Rabat, Morocco, to decide the champions of the 2019–20 Arab Club Champions Cup.
[1] A total of 32 teams competed in the knockout stage.
The tournament was postponed for ten months in 2020 due to the COVID-19 pandemic.
The team that scores more goals on aggregate over the two legs advances to the next round.
If the aggregate score is level, the away goals rule is applied, i.e. the team that scores more goals away from home over the two legs advances.
If away goals are also equal, extra time will not be played and the winners are decided by a penalty shoot-out.
Teams were seeded based on their association rank in their respective region.
Notes Al-Quwa Al-Jawiya won 4–2 on aggregate.
The final was played on 21 August 2021 at the Prince Moulay Abdellah Stadium in Rabat, Morocco.