The Tigers were led by tenth-year head coach Brad Brownell and played their home games at Littlejohn Coliseum in Clemson, South Carolina as members of the Atlantic Coast Conference.

On January 11, 2020, Clemson defeated North Carolina 79–76 in overtime to win their first ever game in Chapel Hill in program history.

Clemson fired assistant coach Steve Smith, for comments made on FBI wire tap in relation to the 2017–18 NCAA Division I men's basketball corruption scandal.

[5] Sources: On August 15, 2018 it was announced that Clemson would represent Team USA in men's basketball at the 2019 Summer Universiade (World University Games) in Naples, Italy.

Clemson, as Team USA, was placed in Pool C with China, Finland, and Ukraine.