The team participated in the Liga MX, Campeón de Campeones, the Campeones Cup, and the CONCACAF Champions League.

Players and squad numbers last updated on 19 January 2020.

[1]Note: Flags indicate national team as has been defined under FIFA eligibility rules.

Players may hold more than one non-FIFA nationality.

Club América will precede their 2019–20 campaign with a series of friendlies to be contested in the United States.