[7][8] A goal from Alan Franco helped them beat Temperley in their opening pre-season friendly on 3 July, which preceded a further victory soon after following strikes from Mauro Molina, Fernando Chávez and Diego Mercado.
[16] Andrés Roa, who had been on loan with Huracán in the past season, was signed on a full-time contract from Deportivo Cali on 12 July.
[19][20] Independiente put eight goals past Aldosivi in pre-season matches on 13 July, though the secondary encounter was against their reserves.
[28][29] Independiente lost to Newell's Old Boys in an opening friendly on 17 July, though responded with a victory later in the day thanks to a Silvio Romero hat-trick.
[34][35] Ecuador's Universidad Católica were defeated in the Copa Sudamericana round of sixteen on 25 July, as Pablo Hernández's goal gave Independiente a first leg advantage.
[40][41] Chilean central midfielder Francisco Silva made a return to his homeland on 2 August, as he agreed a contract with Universidad Católica.
[49] Independiente suffered their fourth competitive loss of 2019–20 on 19 August, as they conceded three unanswered goals away to Estudiantes in the Primera División.
[51] Independiente progressed through to the round of sixteen in the Copa Argentina on 28 August, eliminating Patronato after a narrow one-goal victory at the Estadio Único de Villa Mercedes.
[114] Win Draw Loss Independiente travelled to Villa Domínico for friendlies with Gimnasia y Esgrima on 10 August.
[118] They defeated Universidad Católica, which saw them advance to the quarter-finals where they'd face another trip to Ecuador in Independiente del Valle.