The 2019–20 Melbourne City FC W-League season is the club's fifth season in the W-League, the premier competition for women's football in Australia.

The team is based at the City Football Academy at La Trobe University and play home games at AAMI Park, CB Smith Reserve and ABD Stadium.

Rado Vidošić was head coach of the club for the second consecutive year.

[1] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.