The Cougars, led by first-year head coach Brian Barone, played their home games in the First Community Arena at Vadalabene Center in Edwardsville, Illinois as members of the Ohio Valley Conference.

On March 11, 2019, SIUE announced that coach Jon Harris' contract had not been renewed after a four-year record of 31–88.

[3] Troy Pierce was hired to fill the assistant coach vacancy created by Barone's promotion.

[4] Director of Operations Casey Wyllie left to be an assistant coach at Olney Central College[5] and was replaced by Colin Schneider.

[7] In a vote of conference coaches and sports information directors, SIUE was picked to finish in 10th place in the OVC.