The Knights entered the season as defending champions, and continuing their winning traditions by going undefeated in their first ten games.
The Knights began their playoff campaign with back-to-back sweeps against the Pasay Voyagers and Pampanga Giant Lanterns before meeting in the division finals against the Makati Super Crunch.
Once play resumed in 2021, San Juan would beat Makati by a 77-point lead to advance to the national finals against the rival Davao Occidental Tigers in a rematch of last season's series.
Unfortunately for the Knights, they would lose the series this time around in four games, ending their title defense.
[1] The team played all of their home games this season at the Filoil Flying V Centre.