[4][5] The club agreed, in principle, to the transfers of Unión Santa Fe brothers Bruno and Mauro Pittón on 21 June; subject to terms and medicals.
[7][8] On 24 June, San Lorenzo announced the signing of Ezequiel Cerutti; days after the winger had terminated his contract with Al-Hilal of the Saudi Professional League.
[15][16] Rodrigo De Ciancio departed San Lorenzo for Atlanta on 29 June, a day prior to Santiago González heading to Nueva Chicago on loan.
[22] Adam Bareiro became San Lorenzo's seventh reinforcement, as he penned a one-year loan deal, with a purchase option, from Liga MX's Monterrey.
[32][33] Tomás Conechny was signed permanently by Major League Soccer's Portland Timbers on 22 July, after spending the past twelve months on loan in the United States.
[35] San Lorenzo played the first leg of their Copa Libertadores round of sixteen tie with Cerro Porteño of Paraguay on 24 July, with the encounter ending in a goalless draw in Buenos Aires.
[37][38] San Lorenzo started their league season with a win over Godoy Cruz on 27 July, with Nicolás Blandi securing the points with a late penalty.
[40][41] Gonzalo Castellani became the eighth player to leave San Lorenzo on 30 July, as he agreed terms with Atlético Tucumán.
[56][57] San Lorenzo continued their undefeated streak in the Primera División on 23 August, as well as ending the perfect start of Arsenal de Sarandí at the Estadio Julio Humberto Grondona after strikes from Juan Ramírez and Nicolás Blandi.
[58] San Lorenzo maintained their unbeaten beginning to the league season with a win over Unión Santa Fe on 31 August.