[2] Spartak Trnava were the defending champions, defeating Žilina in the 2019 final.
Slovan Bratislava won their sixteenth Slovak Cup title, defeating Ružomberok in the final.
Matches which were level after regulation advanced to penalties to determine a winner.
98 matches in the first round were played from 20 July 2019 to 7 August 2019.
[5] 16 matches in the fourth round were played from 24 September 2019 to 16 November 2019.