The 2019–20 Southern Illinois Salukis men's basketball team represented Southern Illinois University Carbondale during the 2019–20 NCAA Division I men's basketball season.

The Salukis were led by first-year head coach Bryan Mullins and played their home games at the Banterra Center (formerly SIU Arena) in Carbondale, Illinois as members of the Missouri Valley Conference.

3 seed in the MVC tournament, the Salukis were upset by No.

[1] In an emotional news conference following the game, Southern Illinois head coach Barry Hinson, announced he was stepping down as the coach of the Salukis.

[2] On March 20, 2019, the school hired former SIU star point guard and Loyola assistant coach Bryan Mullins as head coach.