Led by former Lady Vol Kellie Harper, entering her first year as head coach, the team played their games at Thompson–Boling Arena and were members of the Southeastern Conference.

In the December 12 win against Colorado State, junior Rennia Davis scored her 1,000th career point.

[2] The Lady Vols ended the regular season and received a first-round bye in the SEC tournament, defeated Missouri in the second round, but lost to Kentucky in the quarterfinals.

[5] Harper, who was a point guard during Tennessee's three-peat from 1996 to 1998, was hired as her replacement on April 8, 2019.

[6] The SEC media poll was released on October 15, 2019, with Tennessee predicted to finish sixth.