The 2019–20 season was the 63rd season of Unione Calcio Sampdoria in the Serie A, and their 8th consecutive season in the top-flight.

The club competed in Serie A and the Coppa Italia.

Former Sassuolo and Roma coach Eusebio Di Francesco replaced Marco Giampaolo as head coach on 22 June 2019,[1] with Giampaolo moving to Milan on 19 June.

[2] Last updated: 1 August 2020.

Source: Competitive matches Last updated: 2 August 2020Source: Competitions